Current Limitations and Candidate Potential of 5-HT7 Receptor Antagonism in Psychiatric Pharmacotherapy

Current Limitations and Candidate Potential of 5-HT7 Receptor Antagonism in Psychiatric Pharmacotherapy

Several mood-stabilizing atypical antipsychotics and antidepressants weakly block serotonin (5-HT) receptor type-7 (5-HT7R); however, the contributions of 5-HT7R antagonism to clinical efficacy and pathophysiology are yet to be clarified. A novel mood-stabilizing antipsychotic agent, lurasidone exhi...

Full description

Bibliographic Details
Main Authors: Ruri Okubo, Toshiki Hasegawa, Kouji Fukuyama, Takashi Shiroyama, Motohiro Okada
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Psychiatry
Subjects:
antipsychotics
bipolar disorder (BD)
cognition
lurasidone
schizophrenia
5-HT7
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.623684/full

Similar Items

Similar Items