Development and function of the voltage-gated sodium current in immature mammalian cochlear inner hair cells.

Development and function of the voltage-gated sodium current in immature mammalian cochlear inner hair cells.

Inner hair cells (IHCs), the primary sensory receptors of the mammalian cochlea, fire spontaneous Ca(2+) action potentials before the onset of hearing. Although this firing activity is mainly sustained by a depolarizing L-type (Ca(V)1.3) Ca(2+) current (I(Ca)), IHCs also transiently express a large...

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Bibliographic Details
Main Authors: Tobias Eckrich, Ksenya Varakina, Stuart L Johnson, Christoph Franz, Wibke Singer, Stephanie Kuhn, Marlies Knipper, Matthew C Holley, Walter Marcotti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3446918?pdf=render

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