Genome-wide identification of conserved intronic non-coding sequences using a Bayesian segmentation approach

Genome-wide identification of conserved intronic non-coding sequences using a Bayesian segmentation approach

Abstract Background Computational identification of non-coding RNAs (ncRNAs) is a challenging problem. We describe a genome-wide analysis using Bayesian segmentation to identify intronic elements highly conserved between three evolutionarily distant vertebrate species: human, mouse and zebrafish. We...

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Bibliographic Details
Main Authors: Manjula Algama, Edward Tasker, Caitlin Williams, Adam C. Parslow, Robert J. Bryson-Richardson, Jonathan M. Keith
Format: Article
Language:English
Published: BMC 2017-03-01
Series:BMC Genomics
Subjects:
ncRNA
Conserved non-coding sequences
Putative functional elements
Genome segmentation
Bayesian modelling
Online Access:http://link.springer.com/article/10.1186/s12864-017-3645-2

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