Importância do metabolismo no planejamento de fármacos The importance of metabolism in drug design
<abstract language="eng">It is widely recognized that pharmacokinetic optimization needs to be addressed early in drug discovery to reduce the high failure rate in bringing drugs to market. Poor absorption, too short duration of action due to high elimination rate, or the presence of...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2007-02-01
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| Series: | Química Nova |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000100029 |