The extracellular matrix regulates cortical layer dynamics and cross-columnar frequency integration in the auditory cortex

El-Tabbal et al removed the extracellular matrix (ECM) in the primary auditory cortex of Mongolian gerbils and assessed both spontaneous and elicited neural activity. They show that ECM degradation alters translaminar cortical network dynamics and they consider its role in neural plasticity.

Bibliographic Details
Main Authors: Mohamed El-Tabbal, Hartmut Niekisch, Julia U. Henschke, Eike Budinger, Renato Frischknecht, Matthias Deliano, Max F. K. Happel
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01837-4