Completion of draft bacterial genomes by long-read sequencing of synthetic genomic pools

Completion of draft bacterial genomes by long-read sequencing of synthetic genomic pools

Abstract Background Illumina technology currently dominates bacterial genomics due to its high read accuracy and low sequencing cost. However, the incompleteness of draft genomes generated by Illumina reads limits their application in comprehensive genomics analyses. Alternatively, hybrid assembly u...

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Bibliographic Details
Main Authors: Hooman Derakhshani, Steve P. Bernier, Victoria A. Marko, Michael G. Surette
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Genomics
Subjects:
De novo assembly
Bacterial genomics
Hybrid assembly
Synthetic genomic pool
Online Access:http://link.springer.com/article/10.1186/s12864-020-06910-6

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