Acid reflux directly causes sleep disturbances in rat with chronic esophagitis.

Acid reflux directly causes sleep disturbances in rat with chronic esophagitis.

BACKGROUND & AIMS: Gastroesophageal reflux disease (GERD) is strongly associated with sleep disturbances. Proton pump inhibitor (PPI) therapy improves subjective but not objective sleep parameters in patients with GERD. This study aimed to investigate the association between GERD and sleep, and...

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Main Authors: Kenichi Nakahara, Yasuhiro Fujiwara, Takuya Tsukahara, Hirokazu Yamagami, Tetsuya Tanigawa, Masatsugu Shiba, Kazunari Tominaga, Toshio Watanabe, Yoshihiro Urade, Tetsuo Arakawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4162547?pdf=render

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