Peripheral nerve magnetic stimulation: influence of tissue non-homogeneity

<p>Abstract</p> <p>Background</p> <p>Peripheral nerves are situated in a highly non-homogeneous environment, including muscles, bones, blood vessels, etc. Time-varying magnetic field stimulation of the median and ulnar nerves in the carpal region is studied, with specia...

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Main Authors: Papazov Sava P, Krasteva Vessela TZ, Daskalov Ivan K
Format: Article
Language:English
Published: BMC 2003-12-01
Series:BioMedical Engineering OnLine
Online Access:http://www.biomedical-engineering-online.com/content/2/1/19
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spelling doaj-01109bad97f64fbfbbaf22ddb9170d9c2020-11-24T22:16:57ZengBMCBioMedical Engineering OnLine1475-925X2003-12-01211910.1186/1475-925X-2-19Peripheral nerve magnetic stimulation: influence of tissue non-homogeneityPapazov Sava PKrasteva Vessela TZDaskalov Ivan K<p>Abstract</p> <p>Background</p> <p>Peripheral nerves are situated in a highly non-homogeneous environment, including muscles, bones, blood vessels, etc. Time-varying magnetic field stimulation of the median and ulnar nerves in the carpal region is studied, with special consideration of the influence of non-homogeneities.</p> <p>Methods</p> <p>A detailed three-dimensional finite element model (FEM) of the anatomy of the wrist region was built to assess the induced currents distribution by external magnetic stimulation. The electromagnetic field distribution in the non-homogeneous domain was defined as an internal Dirichlet problem using the finite element method. The boundary conditions were obtained by analysis of the vector potential field excited by external current-driven coils.</p> <p>Results</p> <p>The results include evaluation and graphical representation of the induced current field distribution at various stimulation coil positions. Comparative study for the real non-homogeneous structure with anisotropic conductivities of the tissues and a mock homogeneous media is also presented. The possibility of achieving selective stimulation of either of the two nerves is assessed.</p> <p>Conclusion</p> <p>The model developed could be useful in theoretical prediction of the current distribution in the nerves during diagnostic stimulation and therapeutic procedures involving electromagnetic excitation. The errors in applying homogeneous domain modeling rather than real non-homogeneous biological structures are demonstrated. The practical implications of the applied approach are valid for any arbitrary weakly conductive medium.</p> http://www.biomedical-engineering-online.com/content/2/1/19
collection DOAJ
language English
format Article
sources DOAJ
author Papazov Sava P
Krasteva Vessela TZ
Daskalov Ivan K
spellingShingle Papazov Sava P
Krasteva Vessela TZ
Daskalov Ivan K
Peripheral nerve magnetic stimulation: influence of tissue non-homogeneity
BioMedical Engineering OnLine
author_facet Papazov Sava P
Krasteva Vessela TZ
Daskalov Ivan K
author_sort Papazov Sava P
title Peripheral nerve magnetic stimulation: influence of tissue non-homogeneity
title_short Peripheral nerve magnetic stimulation: influence of tissue non-homogeneity
title_full Peripheral nerve magnetic stimulation: influence of tissue non-homogeneity
title_fullStr Peripheral nerve magnetic stimulation: influence of tissue non-homogeneity
title_full_unstemmed Peripheral nerve magnetic stimulation: influence of tissue non-homogeneity
title_sort peripheral nerve magnetic stimulation: influence of tissue non-homogeneity
publisher BMC
series BioMedical Engineering OnLine
issn 1475-925X
publishDate 2003-12-01
description <p>Abstract</p> <p>Background</p> <p>Peripheral nerves are situated in a highly non-homogeneous environment, including muscles, bones, blood vessels, etc. Time-varying magnetic field stimulation of the median and ulnar nerves in the carpal region is studied, with special consideration of the influence of non-homogeneities.</p> <p>Methods</p> <p>A detailed three-dimensional finite element model (FEM) of the anatomy of the wrist region was built to assess the induced currents distribution by external magnetic stimulation. The electromagnetic field distribution in the non-homogeneous domain was defined as an internal Dirichlet problem using the finite element method. The boundary conditions were obtained by analysis of the vector potential field excited by external current-driven coils.</p> <p>Results</p> <p>The results include evaluation and graphical representation of the induced current field distribution at various stimulation coil positions. Comparative study for the real non-homogeneous structure with anisotropic conductivities of the tissues and a mock homogeneous media is also presented. The possibility of achieving selective stimulation of either of the two nerves is assessed.</p> <p>Conclusion</p> <p>The model developed could be useful in theoretical prediction of the current distribution in the nerves during diagnostic stimulation and therapeutic procedures involving electromagnetic excitation. The errors in applying homogeneous domain modeling rather than real non-homogeneous biological structures are demonstrated. The practical implications of the applied approach are valid for any arbitrary weakly conductive medium.</p>
url http://www.biomedical-engineering-online.com/content/2/1/19
work_keys_str_mv AT papazovsavap peripheralnervemagneticstimulationinfluenceoftissuenonhomogeneity
AT krastevavesselatz peripheralnervemagneticstimulationinfluenceoftissuenonhomogeneity
AT daskalovivank peripheralnervemagneticstimulationinfluenceoftissuenonhomogeneity
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