Beta-Cell Mass in Obesity and Type 2 Diabetes, and Its Relation to Pancreas Fat: A Mini-Review

Type 2 diabetes (T2DM) is characterized by insulin resistance and beta-cell dysfunction. Although insulin resistance is assumed to be a main pathophysiological feature of the development of T2DM, recent studies have revealed that a deficit of functional beta-cell mass is an essential factor for the...

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Bibliographic Details
Main Authors: Jun Inaishi, Yoshifumi Saisho
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/12/12/3846