Study of Biokinetic Properties and Optimization of the Conditions of Propagation of Recombinant Asporogenic Strain Producing Anthrax Agent Protective Antigen

Study of Biokinetic Properties and Optimization of the Conditions of Propagation of Recombinant Asporogenic Strain Producing Anthrax Agent Protective Antigen

Recombinant Bacillus anthracis strain 55∆ ТПА-1Spo- passed in vitro preserved its asporogenic property and ability to replicate recombinant plasmid. Synthesis of immunogenic protein by genetically engineered producer did not depend on CO2 content in the atmosphere. Determined were the conditions of...

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Bibliographic Details
Main Authors: S. A. Eremin, N. I. Mikshis, O. A. Volokh, O. M. Kudryavtseva, I. A. Shepelev, A. Yu. Goncharova, Yu. A. Popov, A. K. Nikiforov
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2010-02-01
Series:Проблемы особо опасных инфекций
Subjects:
propagation
<i>bacillus anthracis</i>
protective antigen
Online Access:https://journal.microbe.ru/jour/article/view/514

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