TMP21 in Alzheimer’s Disease: Molecular Mechanisms and a Potential Target

TMP21 in Alzheimer’s Disease: Molecular Mechanisms and a Potential Target

Alzheimer’s disease (AD) is the most common form of dementia in the elderly, which is characterized by progressive cognitive impairment. Neuritic plaques, neurofibrillary tangles and neuronal loss are the major neuropathological hallmarks in AD brains. TMP21 is a key molecule for protein trafficking...

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Bibliographic Details
Main Authors: Kaixin Qiu, Xiaojie Zhang, Shuai Wang, Chunyan Li, Xin Wang, Xuezhi Li, Yili Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Alzheimer’s disease
TMP21
Aβ
Tau phosphorylation
neuronal loss
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00328/full

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