Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses

Systemic amyloidosis is a rare disease that can be rapidly progressive due to widespread organ involvement. There are well-described renal, cardiac, pulmonary, neurological, and dermatologic findings. Here, we outline one patient’s experience with the condition from presentation to making the diagno...

Full description

Bibliographic Details
Main Authors: Andrew Kelsey, MD, Diane H. Smith, MD, Joyce Meng, MD, Michael Murphy, MD, Marti J. Rothe, MD
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:International Journal of Women's Dermatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352647515000684
id doaj-00e7aa178e4a4ca2bb783b4f43cb0ddc
record_format Article
spelling doaj-00e7aa178e4a4ca2bb783b4f43cb0ddc2020-11-25T01:58:49ZengElsevierInternational Journal of Women's Dermatology2352-64752016-03-01211822Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymosesAndrew Kelsey, MD0Diane H. Smith, MD1Joyce Meng, MD2Michael Murphy, MD3Marti J. Rothe, MD4Department of Dermatology, University of Connecticut Health Center, Farmington, ConnecticutDepartment of Dermatology, University of Connecticut Health Center, Farmington, ConnecticutDepartment of Dermatology, University of Connecticut Health Center, Farmington, ConnecticutDepartment of Dermatology, University of Connecticut Health Center, Farmington, ConnecticutCorresponding Author.; Department of Dermatology, University of Connecticut Health Center, Farmington, ConnecticutSystemic amyloidosis is a rare disease that can be rapidly progressive due to widespread organ involvement. There are well-described renal, cardiac, pulmonary, neurological, and dermatologic findings. Here, we outline one patient’s experience with the condition from presentation to making the diagnosis. She presented with pathognomonic dermatologic findings including pinch purpura and ecchymoses found in the skin folds. Key words: apple-green birefringence, amyloid, amyloidosis, Congo red, inframammary erosions, periorbital ecchymoses, pinch purpura, plasma-cell dyscrasia, serum protein electrophoresishttp://www.sciencedirect.com/science/article/pii/S2352647515000684
collection DOAJ
language English
format Article
sources DOAJ
author Andrew Kelsey, MD
Diane H. Smith, MD
Joyce Meng, MD
Michael Murphy, MD
Marti J. Rothe, MD
spellingShingle Andrew Kelsey, MD
Diane H. Smith, MD
Joyce Meng, MD
Michael Murphy, MD
Marti J. Rothe, MD
Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses
International Journal of Women's Dermatology
author_facet Andrew Kelsey, MD
Diane H. Smith, MD
Joyce Meng, MD
Michael Murphy, MD
Marti J. Rothe, MD
author_sort Andrew Kelsey, MD
title Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses
title_short Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses
title_full Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses
title_fullStr Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses
title_full_unstemmed Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses
title_sort amyloidosis: a story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses
publisher Elsevier
series International Journal of Women's Dermatology
issn 2352-6475
publishDate 2016-03-01
description Systemic amyloidosis is a rare disease that can be rapidly progressive due to widespread organ involvement. There are well-described renal, cardiac, pulmonary, neurological, and dermatologic findings. Here, we outline one patient’s experience with the condition from presentation to making the diagnosis. She presented with pathognomonic dermatologic findings including pinch purpura and ecchymoses found in the skin folds. Key words: apple-green birefringence, amyloid, amyloidosis, Congo red, inframammary erosions, periorbital ecchymoses, pinch purpura, plasma-cell dyscrasia, serum protein electrophoresis
url http://www.sciencedirect.com/science/article/pii/S2352647515000684
work_keys_str_mv AT andrewkelseymd amyloidosisastoryofhowinframammaryerosionseclipsedinconspicuousperiorbitalecchymoses
AT dianehsmithmd amyloidosisastoryofhowinframammaryerosionseclipsedinconspicuousperiorbitalecchymoses
AT joycemengmd amyloidosisastoryofhowinframammaryerosionseclipsedinconspicuousperiorbitalecchymoses
AT michaelmurphymd amyloidosisastoryofhowinframammaryerosionseclipsedinconspicuousperiorbitalecchymoses
AT martijrothemd amyloidosisastoryofhowinframammaryerosionseclipsedinconspicuousperiorbitalecchymoses
_version_ 1724967992910938112