Amyloidosis: A story of how inframammary erosions eclipsed inconspicuous periorbital ecchymoses

Systemic amyloidosis is a rare disease that can be rapidly progressive due to widespread organ involvement. There are well-described renal, cardiac, pulmonary, neurological, and dermatologic findings. Here, we outline one patient’s experience with the condition from presentation to making the diagno...

Full description

Bibliographic Details
Main Authors: Andrew Kelsey, MD, Diane H. Smith, MD, Joyce Meng, MD, Michael Murphy, MD, Marti J. Rothe, MD
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:International Journal of Women's Dermatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352647515000684
Description
Summary:Systemic amyloidosis is a rare disease that can be rapidly progressive due to widespread organ involvement. There are well-described renal, cardiac, pulmonary, neurological, and dermatologic findings. Here, we outline one patient’s experience with the condition from presentation to making the diagnosis. She presented with pathognomonic dermatologic findings including pinch purpura and ecchymoses found in the skin folds. Key words: apple-green birefringence, amyloid, amyloidosis, Congo red, inframammary erosions, periorbital ecchymoses, pinch purpura, plasma-cell dyscrasia, serum protein electrophoresis
ISSN:2352-6475