Phylogenomic analysis of vertebrate thrombospondins reveals fish-specific paralogues, ancestral gene relationships and a tetrapod innovation

Phylogenomic analysis of vertebrate thrombospondins reveals fish-specific paralogues, ancestral gene relationships and a tetrapod innovation

<p>Abstract</p> <p>Background</p> <p>Thrombospondins (TSPs) are evolutionarily-conserved, extracellular, calcium-binding glycoproteins with important roles in cell-extracellular matrix interactions, angiogenesis, synaptogenesis and connective tissue organisation. Five T...

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Bibliographic Details
Main Authors: Adams Josephine C, Bohrer Justin, Chadalavada Seetharam C, McKenzie Patrick
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/6/33

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