Enteric Virome Sensing—Its Role in Intestinal Homeostasis and Immunity

Enteric Virome Sensing—Its Role in Intestinal Homeostasis and Immunity

Pattern recognition receptors (PRRs) sensing commensal microorganisms in the intestine induce tightly controlled tonic signaling in the intestinal mucosa, which is required to maintain intestinal barrier integrity and immune homeostasis. At the same time, PRR signaling pathways rapidly trigger the i...

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Bibliographic Details
Main Authors: Rebecca N. Metzger, Anne B. Krug, Katharina Eisenächer
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Viruses
Subjects:
dendritic cells
macrophages
mononuclear phagocytes
intestinal epithelial cells
type I interferon
intestine
Toll-like receptors
RIG-I-like receptors
microbiome
enteric innate immunity
Online Access:http://www.mdpi.com/1999-4915/10/4/146

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