Insights into the cellular function of YhdE, a nucleotide pyrophosphatase from Escherichia coli.

Insights into the cellular function of YhdE, a nucleotide pyrophosphatase from Escherichia coli.

YhdE, a Maf-like protein in Escherichia coli, exhibits nucleotide pyrophosphatase (PPase) activity, yet its cellular function remains unknown. Here, we characterized the PPase activity of YhdE on dTTP, UTP and TTP and determined two crystal structures of YhdE, revealing 'closed' and '...

Full description

Bibliographic Details
Main Authors:	Jin Jin, Ruijuan Wu, Jia Zhu, Shaoyuan Yang, Zhen Lei, Nan Wang, Vinay K Singh, Jimin Zheng, Zongchao Jia
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4319933?pdf=render

Similar Items

A new method to investigate the catalytic mechanism of YhdE pyrophosphatase by using a pyrophosphate fluorescence probe
by: Qingya Shen, et al.
Published: (2017-08-01)

Molecular Dynamics Simulation Studies of dTTP Binding and Catalysis Mediated by YhdE Dimerization.
by: Nan Wang, et al.
Published: (2015-01-01)

Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP
by: Angela M. Mitchell, et al.
Published: (2018-08-01)

Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1
by: Kazuki Kato, et al.
Published: (2018-10-01)

Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication.
by: Fabio Lapenta, et al.
Published: (2016-01-01)

Correction: Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication.
by: PLOS ONE Staff
Published: (2016-01-01)

Purine Nucleotide Metabolism in Escherichia Coli
by: Finkler, A.
Published: (1978)

Conformational Plasticity of the Active Site Entrance in <i>E. coli</i> Aspartate Transcarbamoylase and Its Implication in Feedback Regulation
by: Zhen Lei, et al.
Published: (2020-01-01)

Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation
by: Nita R. Shah, et al.
Published: (2017-05-01)

The Ruegeria pomeroyi acuI gene has a role in DMSP catabolism and resembles yhdH of E. coli and other bacteria in conferring resistance to acrylate.
by: Jonathan D Todd, et al.
Published: (2012-01-01)

Structural characterization of the mitochondrial Ca2+ uniporter provides insights into Ca2+ uptake and regulation
by: Wenping Wu, et al.
Published: (2021-08-01)

The Biochemical Genetics of Purine Nucleotide Synthesis in Escherichia Coli
by: Watson, M. D.
Published: (1977)

Purification of Maize Nucleotide Pyrophosphatase/Phosphodiesterase Casts Doubt on the Existence of Zeatin Cis–Trans Isomerase in Plants
by: Tomáš Hluska, et al.
Published: (2017-08-01)

Development of biosensors for pyrophosphatase detection
by: Liao, Chi-Hsiang, et al.
Published: (2016)

Lack of Vacuolar H+ -Pyrophosphatase and Cytosolic Pyrophosphatases Causes Fatal Developmental Defects in Arabidopsis thaliana
by: Mayu Fukuda, et al.
Published: (2020-05-01)

Palladium-catalyzed synthesis and nucleotide pyrophosphatase inhibition of benzo[4,5]furo[3,2-b]indoles
by: Hoang Huy Do, et al.
Published: (2019-11-01)

Structural and functional studies of the pyridine nucleotide transhydrogenase of Escherichia coli
by: Glavas, Natalie Ann
Published: (2009)

Structural and functional studies of the pyridine nucleotide transhydrogenase of Escherichia coli
by: Glavas, Natalie Ann
Published: (2009)

Pyridine nucleotide transhydrogenase of Escherichia coli: nucleotide sequence of the pnt gene and characterization of the enzyme complex
by: Clarke, David Morgan
Published: (2010)

Structural and Functional Studies of Escherichia coli Kinases and Phosphatases
by: Zheng, JIMIN
Published: (2009)

The characterization of vacuolar pyrophosphatase expression in sugarcane
by: Swart, Johannes Cornelius
Published: (2008)

The cloning and nucleotide sequence of the pyruvate dehydrogenase complex genes of Escherichia coli
by: Stephens, Paul Edward
Published: (1982)

A crystallographic study of the inorganic pyrophosphatase from Bacillus subtilis : the first in a new family of inorganic pyrophosphatases
by: Milner, Andrew John
Published: (2001)

Bioseparation of Four Proteins from Euphorbia characias Latex: Amine Oxidase, Peroxidase, Nucleotide Pyrophosphatase/Phosphodiesterase, and Purple Acid Phosphatase
by: Rosaria Medda, et al.
Published: (2011-01-01)

The hepatic ectonucleotide pyrophosphatase/phosphodiesterase 1 gene mRNA abundance is reduced by insulin and induced by dexamethasone
by: Huiwen Ma, et al.
Published: (2018-03-01)

The pyrimidine nucleotide biosynthetic pathway modulates production of biofilm determinants in Escherichia coli.
by: Marco Garavaglia, et al.
Published: (2012-01-01)

The role of the purine nucleotide pools in escherichia coli in the control of nucleic acid synthesis
by: Jeffries, G. A.
Published: (1971)

Structural and Biochemical Characterization of Apicomplexan Inorganic Pyrophosphatases
by: Abhishek Jamwal, et al.
Published: (2017-07-01)

Inactivation of yeast inorganic pyrophosphatase by organic solvents
by: Rodrigo Grazinoli-Garrido, et al.
Published: (2004-12-01)

Multiple facets of H+-pyrophosphatase and related enzymes
by: Ali Ferjani, et al.
Published: (2016-08-01)

Properties of the Inorganic Pyrophosphatase from Desulfovibrio Desulfuricans
by: Ware, D. A.
Published: (1972)

Mimicry of cellular signalling pathways by enteropathogenic Escherichia coli
by: Phillips, Neil
Published: (2006)

Characterization of DicB by partially masking its potent inhibitory activity of cell division
by: Shaoyuan Yang, et al.
Published: (2016-01-01)

Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism.
by: Shannon E Hill, et al.
Published: (2017-01-01)

Intestinal Pathogenic Escherichia coli: Insights for Vaccine Development
by: Maricarmen Rojas-Lopez, et al.
Published: (2018-03-01)

Insights into the Stress Response Triggered by Kasugamycin in Escherichia coli
by: Christian Müller, et al.
Published: (2016-06-01)

Novel Insights in Structure and Mechanism of Escherichia coli Transketolase
by: Rabe von Pappenheim, Fabian
Published: (2018)

Mining the within-motif nucleotide dependence of transcription factor binding sites in Escherichia coli
by: Chi Yang, et al.
Published: (2016)

Rôle des microdomaines membranaires dans le ciblage apical de la nucléotide pyrophosphatase NPP3 dans les cellules MDCK
by: Delaunay, Jean-Louis
Published: (2007)

Studies on the Cellular Localization and Thermostability of Ovalbumin Produced in Escherichia coli
by: Arii, Yasuhiro
Published: (2009)