cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts

cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts

ATP-binding cassette transporter A1 (ABC22222222222263) plays a crucial role in apoA-I lipidation, a key step in reverse cholesterol transport. cAMP induces apoA-I binding activity and promotes cellular cholesterol efflux. We investigated the role of the cAMP/protein kinase A (PKA) dependent pathway...

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Bibliographic Details
Main Authors: Bassam Haidar, Maxime Denis, Larbi Krimbou, Michel Marcil, Jacques Genest, Jr.
Format: Article
Language:English
Published: Elsevier 2002-12-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein A-I
high density lipoprotein
PKA
protein kinase A
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032736X

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