APOE2 promotes the development and progression of subretinal neovascularization in age-related macular degeneration via MAPKs signaling pathway

APOE2 promotes the development and progression of subretinal neovascularization in age-related macular degeneration via MAPKs signaling pathway

Background: Neovascular age-related macular degeneration (nvAMD) is one of the main pathological features of wet AMD. Apolipoprotein E2 is involved in the formation of nvAMD but the molecular mechanism has not been reported. Methods: The APOE alleles in AMD patients were detected by genotyping. Mous...

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Bibliographic Details
Main Authors: Yiwen Sun, Ruixia Song, Yanliang Ai, Jianjun Zhu, Jun He, Minyan Dang, Hui Li
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Saudi Journal of Biological Sciences
Subjects:
APOE2
nvAMD
MAPKs pathway
Inflammatory cytokines
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X2030276X

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