A mechanistic study of Toxoplasma gondii ROP18 inhibiting differentiation of C17.2 neural stem cells

A mechanistic study of Toxoplasma gondii ROP18 inhibiting differentiation of C17.2 neural stem cells

Abstract Background Congenital infection of Toxoplasma gondii is an important factor causing birth defects. The neural stem cells (NSCs) are found to be one of the target cells for the parasite during development of the brain. As a key virulence factor of the parasite that hijacks host cellular func...

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Bibliographic Details
Main Authors: Xian Zhang, Rui Su, Zhengyang Cheng, Wanbo Zhu, Yelin Li, Yongzhong Wang, Jian Du, Yihong Cai, Qingli Luo, Jilong Shen, Li Yu
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Parasites & Vectors
Subjects:
T. gondii
Neural stem cells
C17.2
Differentiation
ROP18
Online Access:http://link.springer.com/article/10.1186/s13071-017-2529-2

Internet

http://link.springer.com/article/10.1186/s13071-017-2529-2

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