Absence of Foxp3+ regulatory T cells during allergen provocation does not exacerbate murine allergic airway inflammation.

Absence of Foxp3+ regulatory T cells during allergen provocation does not exacerbate murine allergic airway inflammation.

Regulatory T cells (Tregs) play a non-redundant role in maintenance of immune homeostasis. This is achieved by suppressing both, priming of naïve cells and effector cell functions. Although Tregs have been implicated in modulating allergic immune responses, their influence on distinct phases of deve...

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Bibliographic Details
Main Authors: Abdul Mannan Baru, Venkateswaran Ganesh, Jayendra Kumar Krishnaswamy, Christina Hesse, Christopher Untucht, Silke Glage, Georg Behrens, Christian Thomas Mayer, Franz Puttur, Tim Sparwasser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3468440?pdf=render

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