A clinical analysis of the effectiveness of combined treatment of retinal macular edema

• Main Authors: A. -G. Aliev, A. M. Magomedova, A. A.-G. Aliev, S. I. Zakieva, M. M. Mikailova
• Format: Article
• Language: Russian
• Published: Real Time Ltd 2018-10-01
• Series: Российский офтальмологический журнал
• Subjects: макулярный отек; кортикостероиды; ингибиторы неоангиогенеза; лазерная коагуляция сетчатки; macular edema; corticosteroids; inhibitors of neoangiogenesis; laser photocoagulation of the retina
• Online Access: https://roj.igb.ru/jour/article/view/68

Purpose: to assess the effectiveness of combined treatment of macular edema (ME) of varied etiology. Materials and methods. The results of combined treatment of 32 patients (38 eyes) aged 55 to 75. Of these, 13 patients (15 eyes) had postocclusion MO, 12 patients (14 eyes) had diabetic MO and 7 patients (9 eyes) had an exudate form of age-related maculardegeneration. Two groups of patients were formed depending on the treatment administered. Group 1 (14 patients) intravitreally received an inhibitor of neoangiogenesis, Ranibizumab, whilst group 2 (18 patients) received combined treatment which included a prolonged corticosteroid (Diprospan) administered into sub-Tenon’s space, laser coagulation and intravitreal administration of Ranibizumab. All patients underwent high-definition optical coherent tomography examinations (HDOCT, OCT 4.000 Cirrus Humphrey - Zeiss, San Leandro, USA) and computer tonometry, performed on a visual field analyzer Peritest 30/50/100 using the Macula software. Results. The combined treatment of patients with ME resulted in a stable improvement of visual acuity (averagely by 0.55 in 88 % of cases), rapid retinal edema reduction (its thinning) in 74 % of cases, reduction of risk of neovascular complications, and stabilization of the results achieved. Conclusion. Due to a number of components involved and pathogenetic emphasis, the combined treatment promotes the effectiveness of functional rehabilitation of patients with ME of varied origin // Russian Ophthalmological Journal, 2017; 1: 5-8. doi: 10.21516/2072-0076-2017-10-1-5-8