Therapeutic potential of DNA methyltransferase inhibitors with immune checkpoint inhibitor therapy in breast cancer

Therapeutic potential of DNA methyltransferase inhibitors with immune checkpoint inhibitor therapy in breast cancer

Immune checkpoint inhibitor (ICI) therapy has changed the landscape of cancer treatment, particularly for high-mutation burden cancers. However, ICI therapy has thus far demonstrated limited efficacy in breast cancers, where tumor mutation rates are intermediate. Nonetheless, because of limited but...

Full description

Bibliographic Details
Main Authors: Na Luo, Ayaka Sugiura, Justin M. Balko
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-03-01
Series:Cell Stress
Subjects:
epigenetic
DNA methyltransferase
immunotherapy
PD-L1
NFkB
cytotoxic T cells
MHC
Online Access:http://www.cell-stress.com/researcharticles/therapeutic-potential-of-dna-methyltransferase-inhibitors-with-immune-checkpoint-inhibitor-therapy-in-breast-cancer/

Internet

http://www.cell-stress.com/researcharticles/therapeutic-potential-of-dna-methyltransferase-inhibitors-with-immune-checkpoint-inhibitor-therapy-in-breast-cancer/

Similar Items