Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells

Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells

MicroRNAs in small extracellular vesicle (sEV-miRNAs) have been widely investigated as crucial regulated molecules secreted by tumor cells to communicate with surroundings. It is of great significance to explore the loading mechanism of sEV-miRNAs by tumor cells. Here, we comprehensively illustrated...

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Bibliographic Details
Main Authors: Yangyang Li, Jian Zhang, Sha Li, Chongye Guo, Qian Li, Xin Zhang, Meng Li, Shuangli Mi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
miRNA—microRNA
SUMOylation
extracellular vesicles
RNA binding protein
sorting mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.687912/full

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