SwarmDock and the Use of Normal Modes in Protein-Protein Docking

Here is presented an investigation of the use of normal modes in protein-protein docking, both in theory and in practice. Upper limits of the ability of normal modes to capture the unbound to bound conformational change are calculated on a large test set, with particular focus on the binding interfa...

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Bibliographic Details
Main Authors: Paul A. Bates, Iain H. Moal
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:International Journal of Molecular Sciences
Subjects:
PSO
RTB
Online Access:http://www.mdpi.com/1422-0067/11/10/3623/