A balanced review of the status T cell-based therapy against cancer
<p>Abstract</p> <p>A recent commentary stirred intense controversy over the status of anti-cancer immunotherapy. The commentary suggested moving beyond current anti-cancer vaccines since active-specific immunization failed to match expectations toward a more aggressive approach inv...
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| Format: | Article |
| Language: | English |
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BMC
2005-04-01
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| Series: | Journal of Translational Medicine |
| Online Access: | http://www.translational-medicine.com/content/3/1/16 |
| Summary: | <p>Abstract</p> <p>A recent commentary stirred intense controversy over the status of anti-cancer immunotherapy. The commentary suggested moving beyond current anti-cancer vaccines since active-specific immunization failed to match expectations toward a more aggressive approach involving the adoptive transfer of in vitro expanded tumor antigen-specific T cells. Although the same authors clarified their position in response to others' rebuttal more discussion needs to be devoted to the current status of T cell-based anti-cancer therapy. The accompanying publications review the status of adoptive transfer of cancer vaccines on one hand and active-specific immunization on the other. Hopefully, reading these articles will offer a balanced view of the current status of antigen-specific ant-cancer therapies and suggest future strategies to foster unified efforts to complement either approach with the other according to specific biological principles.</p> |
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| ISSN: | 1479-5876 |