Using bosentan to treat paraquat poisoning-induced acute lung injury in rats.

Paraquat poisoning is well known for causing multiple organ function failure (MODS) and high mortality. Acute lung injury and advanced pulmonary fibrosis are the most serious complications. Bosentan is a dual endothelin receptor antagonist. It plays an important role in treating PF. There is no rela...

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Bibliographic Details
Main Authors: Zhongchen Zhang, Xiangdong Jian, Wei Zhang, Jieru Wang, Qian Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796527?pdf=render