Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine

Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine

Abstract Mesenchymal stem cell (MSC)-mediated immunomodulation has been harnessed for the treatment of human diseases, but its underlying mechanism has not been fully understood. Dead cells, including apoptotic cells have immunomodulatory properties. It has been repeatedly reported that the proporti...

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Bibliographic Details
Main Authors: Xuemei He, Weiqi Hong, Jingyun Yang, Hong Lei, Tianqi Lu, Cai He, Zhenfei Bi, Xiangyu Pan, Yu Liu, Lunzhi Dai, Wei Wang, Canhua Huang, Hongxin Deng, Xiawei Wei
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00688-z

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