Derivation of Huntington Disease affected Genea046 human embryonic stem cell line

The Genea046 human embryonic stem cell line was derived from a donated, fully commercially consented ART blastocyst, carrying HTT gene CAG expansion of 45 repeats, indicative of Huntington Disease. Following ICM outgrowth on inactivated human feeders, karyotype was confirmed as 46, XX by CGH and STR...

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Bibliographic Details
Main Authors: Biljana Dumevska, Omar Chami, Robert McKernan, Divya Goel, Uli Schmidt
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116000635