Read length and repeat resolution: exploring prokaryote genomes using next-generation sequencing technologies.

BACKGROUND: There are a growing number of next-generation sequencing technologies. At present, the most cost-effective options also produce the shortest reads. However, even for prokaryotes, there is uncertainty concerning the utility of these technologies for the de novo assembly of complete genome...

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Bibliographic Details
Main Authors: Matt J Cahill, Claudio U Köser, Nicholas E Ross, John A C Archer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2902515?pdf=render