Insilico Design and Construction of a Chimeric Gene Comprising the A Subunit of Vibrio cholera Pilin and the B Subunit of Cholera Toxin

Insilico Design and Construction of a Chimeric Gene Comprising the A Subunit of Vibrio cholera Pilin and the B Subunit of Cholera Toxin

Background and Aims: Cholera is a lethal diarrheal disease that cause by Vibrio cholerae. Cholera toxin and colonization factor pili (tcpA) are the major virulence factor in V.cholerae pathogenesis. The B subunit of the enterotoxin )ctxB) which is responsible for toxin binding to eukaryotic cells an...

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Bibliographic Details
Main Authors: Milad Amerian, Shahram Nazarian, Hosein Honari, Mohammad Ebrahim Minaie, Emad kordbacheh
Format: Article
Language:English
Published: Farname 2017-08-01
Series:Iranian Journal of Medical Microbiology
Subjects:
Vibrio cholerae
Virulence factors
Cholera toxin
Bioinformatic desigen
Chimeric gene
Online Access:http://ijmm.ir/article-1-665-en.html

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