Cannabidiol (CBD) as a Promising Anti-Cancer Drug

Recently, cannabinoids, such as cannabidiol (CBD) and Δ<sup>9</sup> -tetrahydrocannabinol (THC), have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a wide array of organic molecules, including those that are physiologically produced in humans, synthesi...

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Main Authors:	Emily S. Seltzer, Andrea K. Watters, Danny MacKenzie, Lauren M. Granat, Dong Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	Cancers
Subjects:	Cannbinoids Cannabidiol CBD anti-cancer drug
Online Access:	https://www.mdpi.com/2072-6694/12/11/3203

id	doaj-005f00dc735d498686eaafc2b6830464
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spelling	doaj-005f00dc735d498686eaafc2b68304642020-11-25T04:04:33ZengMDPI AGCancers2072-66942020-10-01123203320310.3390/cancers12113203Cannabidiol (CBD) as a Promising Anti-Cancer DrugEmily S. Seltzer0Andrea K. Watters1Danny MacKenzie2Lauren M. Granat3Dong Zhang4Department of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, NY 11568, USADepartment of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, NY 11568, USADepartment of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, NY 11568, USADepartment of Internal Medicine, Cleveland Clinic, Cleveland, OH, 44195, USADepartment of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, NY 11568, USARecently, cannabinoids, such as cannabidiol (CBD) and Δ<sup>9</sup> -tetrahydrocannabinol (THC), have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a wide array of organic molecules, including those that are physiologically produced in humans, synthesized in laboratories, and extracted primarily from the <i>Cannabis sativa</i> plant. These organic molecules share similarities in their chemical structures as well as in their protein binding profiles. However, pronounced differences do exist in their mechanisms of action and clinical applications, which will be briefly compared and contrasted in this review. The mechanism of action of CBD and its potential applications in cancer therapy will be the major focus of this review article.https://www.mdpi.com/2072-6694/12/11/3203CannbinoidsCannabidiolCBDanti-cancer drug
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Emily S. Seltzer Andrea K. Watters Danny MacKenzie Lauren M. Granat Dong Zhang
spellingShingle	Emily S. Seltzer Andrea K. Watters Danny MacKenzie Lauren M. Granat Dong Zhang Cannabidiol (CBD) as a Promising Anti-Cancer Drug Cancers Cannbinoids Cannabidiol CBD anti-cancer drug
author_facet	Emily S. Seltzer Andrea K. Watters Danny MacKenzie Lauren M. Granat Dong Zhang
author_sort	Emily S. Seltzer
title	Cannabidiol (CBD) as a Promising Anti-Cancer Drug
title_short	Cannabidiol (CBD) as a Promising Anti-Cancer Drug
title_full	Cannabidiol (CBD) as a Promising Anti-Cancer Drug
title_fullStr	Cannabidiol (CBD) as a Promising Anti-Cancer Drug
title_full_unstemmed	Cannabidiol (CBD) as a Promising Anti-Cancer Drug
title_sort	cannabidiol (cbd) as a promising anti-cancer drug
publisher	MDPI AG
series	Cancers
issn	2072-6694
publishDate	2020-10-01
description	Recently, cannabinoids, such as cannabidiol (CBD) and Δ<sup>9</sup> -tetrahydrocannabinol (THC), have been the subject of intensive research and heavy scrutiny. Cannabinoids encompass a wide array of organic molecules, including those that are physiologically produced in humans, synthesized in laboratories, and extracted primarily from the <i>Cannabis sativa</i> plant. These organic molecules share similarities in their chemical structures as well as in their protein binding profiles. However, pronounced differences do exist in their mechanisms of action and clinical applications, which will be briefly compared and contrasted in this review. The mechanism of action of CBD and its potential applications in cancer therapy will be the major focus of this review article.
topic	Cannbinoids Cannabidiol CBD anti-cancer drug
url	https://www.mdpi.com/2072-6694/12/11/3203
work_keys_str_mv	AT emilysseltzer cannabidiolcbdasapromisinganticancerdrug AT andreakwatters cannabidiolcbdasapromisinganticancerdrug AT dannymackenzie cannabidiolcbdasapromisinganticancerdrug AT laurenmgranat cannabidiolcbdasapromisinganticancerdrug AT dongzhang cannabidiolcbdasapromisinganticancerdrug
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Cannabidiol (CBD) as a Promising Anti-Cancer Drug

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