Assessment of “Sameness” and/or Differences between Marketed Creams Containing Miconazole Nitrate Using a Discriminatory in vitro<i> </i>Release Testing (IVRT) Method

Assessment of “Sameness” and/or Differences between Marketed Creams Containing Miconazole Nitrate Using a Discriminatory in vitro<i> </i>Release Testing (IVRT) Method

In vitro release testing (IVRT) provides an efficient method for the evaluation of drug release from semi-solid formulations. The aim of this research was to develop and validate a discriminatory IVRT system using vertical diffusion cells (VDCs) to assess generic topical products containing miconazo...

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Bibliographic Details
Main Authors: Potiwa Purazi, Seeprarani Rath, Ashmita Ramanah, and Isadore Kanfer
Format: Article
Language:English
Published: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2020-02-01
Series:Scientia Pharmaceutica
Subjects:
ivrt
vertical diffusion cells (vdcs)
miconazole nitrate
topical dermatological creams
fda supac-ss guidance
acceptance criteria
method validation
discriminatory ability
q1/q2/q3 properties.
Online Access:https://www.mdpi.com/2218-0532/88/1/6

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