Tumor Heterogeneity in Glioblastomas: From Light Microscopy to Molecular Pathology

Tumor Heterogeneity in Glioblastomas: From Light Microscopy to Molecular Pathology

One of the main reasons for the aggressive behavior of glioblastoma (GBM) is its intrinsic intra-tumor heterogeneity, characterized by the presence of clonal and subclonal differentiated tumor cell populations, glioma stem cells, and components of the tumor microenvironment, which affect multiple ha...

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Bibliographic Details
Main Authors: Aline P. Becker, Blake E. Sells, S. Jaharul Haque, Arnab Chakravarti
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
glioblastoma
tumor microenvironment
precision medicine
glioma
neoplastic stem cells
prognosis
Online Access:https://www.mdpi.com/2072-6694/13/4/761

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