Compensatory evolution of gene regulation in response to stress by Escherichia coli lacking RpoS.

The RpoS sigma factor protein of Escherichia coli RNA polymerase is the master transcriptional regulator of physiological responses to a variety of stresses. This stress response comes at the expense of scavenging for scarce resources, causing a trade-off between stress tolerance and nutrient acquis...

Full description

Bibliographic Details
Main Authors: Daniel M Stoebel, Karsten Hokamp, Michael S Last, Charles J Dorman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2744996?pdf=render