Research progress of monocyte/high density lipoprotein ratio in cardiovascular diseases

• Main Authors: Wan-Yue Sang, Hong-Jian Li
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2021-05-01
• Series: Journal of Hainan Medical University
• Subjects: monocyte to high density lipoprotein cholesterol ratio; cardiovascular diseases; inflammation
• Online Access: http://www.hnykdxxb.com/PDF/202110/14.pdf

In recent years, monocyte to high density lipoprotein cholesterol ratio (MHR) has attracted wide attention as a new marker of inflammatory response. This indicator includes two aspects: inflammatory response and lipid accumulation, which are the two most basic characteristics of Atherosclerosis (AS). AS is closely related to the occurrence of Cardiovascular diseases (CVD). A large number of existing studies have confirmed that MHR is an inflammatory marker that can dynamically reflect the trend of inflammation, can reflect the chronic inflammatory response in blood vessels, and can evaluate the occurrence, development and prognosis of cardiovascular disease in a non-invasive manner. This article reviews recent studies on the role of monocytes and high-density lipoproteins in chronic inflammation of blood vessels, as well as the current status of research on MHR and cardiovascular disease in the light of recent literature.