A patient-like swine model of gastrointestinal fibrotic strictures for advancing therapeutics

Abstract Gastrointestinal (GI) strictures are difficult to treat in a variety of disease processes. Currently, there are no Food and Drug Administration (FDA) approved drugs for fibrosis in the GI tract. One of the limitations to developing anti-fibrotic drugs has been the lack of a reproducible, re...

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Bibliographic Details
Main Authors: Ling Li, Mohamad I. Itani, Kevan J. Salimian, Yue Li, Olaya Brewer Gutierrez, Haijie Hu, George Fayad, Jean A. Donet, Min Kyung Joo, Laura M. Ensign, Vivek Kumbhari, Florin M. Selaru
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92628-8