Comparative analysis of iron homeostasis in sub-Saharan African children with sickle cell disease and their unaffected siblings

Comparative analysis of iron homeostasis in sub-Saharan African children with sickle cell disease and their unaffected siblings

Iron is an essential trace element subject to tight regulation to ensure adequate running of biological processes. In sub-Saharan Africa where hemoglobinopathies are common, iron homeostasis is likely to be impaired by these conditions. Here we assessed and compared key serum proteins associated wit...

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Bibliographic Details
Main Authors: Selma eGomez, Aïssatou eDiawara, Elias eGbeha, Philip eAwadalla, Ambaliou eSanni, Youssef eIdaghdour, M Cheriff eRahimy
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Pediatrics
Subjects:
Anemia
iron deficiency
iron homeostasis
Sickle Cell Disease
hepcidin
Red blood cell indices
Online Access:http://journal.frontiersin.org/Journal/10.3389/fped.2016.00008/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fped.2016.00008/full

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