Maternal High Fat Diet Alters Gut Microbiota of Offspring and Exacerbates DSS-Induced Colitis in Adulthood

Maternal High Fat Diet Alters Gut Microbiota of Offspring and Exacerbates DSS-Induced Colitis in Adulthood

Background: Accumulating evidence shows that high fat diet is closely associated with inflammatory bowel disease. However, the effects and underlying mechanisms of maternal high fat diet (MHFD) on the susceptibility of offspring to colitis in adulthood lacks confirmation.Methods: C57BL/6 pregnant mi...

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Bibliographic Details
Main Authors: Runxiang Xie, Yue Sun, Jingyi Wu, Shumin Huang, Ge Jin, Zixuan Guo, Yujie Zhang, Tianyu Liu, Xiang Liu, Xiaocang Cao, Bangmao Wang, Hailong Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
maternal high fat diet
offspring
intestinal development
microbiota
colitis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02608/full

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