Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective
Protein biosynthesis is a vital process for all kingdoms of life. The ribosome is the massive ribonucleoprotein machinery that reads the genetic code, in the form of messenger RNA (mRNA), to produce proteins. The mechanism of translation is tightly regulated to ensure that cell growth is well sustai...
Main Authors: | Simone Pellegrino, Salvatore Terrosu, Gulnara Yusupova, Marat Yusupov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/17/4392 |
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