HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages

HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages

<p>Abstract</p> <p>Background</p> <p>Macrophages are important targets and long-lived reservoirs of HIV-1, which are not cleared of infection by currently available treatments. In the primary monocyte-derived macrophage model of infection, replication is initially produ...

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Bibliographic Details
Main Authors: Purcell Damian FJ, Jans David A, Howard Jane L, O'Brien Kate, Tan Chun H, Nasr-Esfahani Somayeh, Dowling Dinushka, Stoltzfus C Martin, Sonza Secondo
Format: Article
Language:English
Published: BMC 2008-02-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/18

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