Prognostic impact of CD34 and SMA in cancer‐associated fibroblasts in stage I–III NSCLC

Abstract Background Epithelial‐to‐mesenchymal transition (EMT) is a crucial step in lung cancer pathogenesis. Among others, cancer‐associated fibroblasts (CAFs) are reported to regulate this process. Objectives To investigate the prognostic and clinical impact, we analyzed CD34+ and SMA+ CAFs in non...

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Bibliographic Details
Main Authors: Arik Bernard Schulze, Lars Henning Schmidt, Birthe Heitkötter, Sebastian Huss, Michael Mohr, Alessandro Marra, Ludger Hillejan, Dennis Görlich, Peter J. Barth, Jan Rehkämper, Georg Evers
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Thoracic Cancer
Subjects:
EMT
SMA
Online Access:https://doi.org/10.1111/1759-7714.13248