CircHIPK3 regulates cardiac fibroblast proliferation, migration and phenotypic switching through the miR-152-3p/TGF-β2 axis under hypoxia

Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia. Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are involved in the regulation of physiological and pathophysiological processes. CircHIPK3 has been identified as the o...

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Bibliographic Details
Main Authors: Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao, Zhijiang Liu, Wenming Chen, Junbo Ge, Bei Shi
Format: Article
Language:English
Published: PeerJ Inc. 2020-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/9796.pdf