A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer

A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer

Background: PIK3CA pathways are the most frequently mutated oncogenic pathway in head and neck squamous cell carcinoma (HNSCC), including virally driven HNCs. PIK3CA is involved in the PI3K-PTEN-mTOR signalling pathway. PIK3CA has been implicated in HNSCC progression and PIK3CA mutations may serve a...

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Bibliographic Details
Main Authors: Henri Schmidt, Arutha Kulasinghe, Richard J.N. Allcock, Lit Yeen Tan, Elisa Mokany, Liz Kenny, Chamindie Punyadeera
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Diagnostics
Subjects:
circulating tumour (ctDNA), liquid biopsies
head and neck squamous cell carcinoma
head and neck cancers
diagnosis
monitoring
Online Access:https://www.mdpi.com/2075-4418/8/4/79

Internet

https://www.mdpi.com/2075-4418/8/4/79

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