New Insights into the Pathogenesis and Therapies of IgA Nephropathy

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine and Nursing; aberrantly glycosylated IgA1; adults; autoantibody; biomarker; body mass index; CD38; children; clinical trials; complement; complement C3; crescents; galactose-deficient IgA1; genetics; glomerular filtration rate; glycosylation of IgA1; IgA; IgA nephropathy; IgA Nephropathy; IgA vasculitis; IgA Vasculitis; IgA1; immune complex; kidney; kidney biopsy; kidney mesangium; KM55; mesangial matrix expansion; mouse model; n/a; nephritis; nephrology; O-glycosylation; obesity; Oxford score; physiopathology; plasma cells; presentation; prognosis; proteinuria; renal pathology; treatment; urinary galactose-deficient IgA1
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication
• Physical Description: 1 online resource (194 p.)
• ISBN: 9783036550411; 9783036550428; books978-3-0365-5042-8
• Access: Open Access

IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a frequent cause of kidney failure. Better understanding of the pathogenesis of IgAN and the related genetic, immunological, and cellular susceptibility factors are needed to enable the development of effective disease-specific therapy. This book brings together international experts to provide clinical and experimental studies and reviews with an emphasis on early diagnosis, prognosis, disease pathogenesis, determination of disease activity, and new strategies for treatment for IgAN.