Redox-Active Molecules as Therapeutic Agents

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Biology, life sciences; Research and information: general; (poly)phenols; adipose-derived mesenchymal stem cell; amniotic membrane-derived mesenchymal stem cell; antioxidant capacity; antioxidants; apoptosis; apurinic/apyrimidinic endonuclease 1; assisted reproductive technology; ATF4; BAPN; bioactivity-based assays; breast cancer; cancer therapy; cardiorenal syndrome; carnosic acid; CD IGS rats; cell cycle; cell invasion; chemoresistance; cisplatin; conditioned medium; curcumin; cyanidin; Cysteamine; cytotoxicity; DNA damage; doxorubicin; E3330; embryo; EMT; glutathione peroxidase; glutathione reductase; GSH; H2S donors; hydrogen sulfide; hypercholesterolemia; in vitro culture; in vitro fertilization; inhibitors; invasion; KEAP1; lactic acid bacteria; lysyl-oxidase; lysyl-oxidase like 2; metabolomics; metastases; migration; mitochondrial reactive oxygen species; N-acetyl cysteine; n/a; non-small cell lung cancer; NRF2; nuclear factor erythroid 2-related factor 2 (Nrf2); oxidative stress; OxPhos; peroxiredoxin 3; pro-oxidant therapy; prostate cancer; reactive oxygen species; redox signaling; Rubus genus; selenium-enriched Enterococcus faecium; selenium-enriched Streptococcus thermophilus; SGK1; sildenafil; systemic sclerosis; thiostrepton; thiosulfate; verbascoside; withanolide; yeast-based discovery platform
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication
• Physical Description: 1 online resource (266 p.)
• ISBN: 9783036543819; 9783036543826; books978-3-0365-4382-6
• Access: Open Access

Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of research by providing novel mechanistic insights. This book compiles a collection of 13 articles, covering a range of topics from in vitro studies to clinical research, focused on the potential therapeutic effects of either natural or synthetic compounds, applicable to different redox-related diseases.