Osteoarthritis: From Molecular Pathways to Therapeutic Advances

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Biology, life sciences; Research and information: general; adipokines; aging; angiogenesis; autophagy; biomarker; cartilage; cartilage trauma; celecoxib; cell death; chemokines; chondrocyte; chondrocytes; chondrocytic commitment; chondroitin; chondroprotection; collagen; cytokines; dietary supplements; early diagnosis; ECM; exercise; glucosamine; glucosamine sulfate; hexosamine biosynthetic pathway; hyaluronic acid; hydrostatic pressure; hypertrophy; IFNγ, IL-17; IL-1β; IL-4; inflammaging; inflammation; infrared spectroscopy; inhibitor; Interleukin-1β; joint modelling; linker modifications; matrix metalloproteinases; mechanical loading; meniscus; mesenchimal stem cells; methylsulfonylmethane; microRNA; miRNAs; mitochondrial dysfunction; MMP-13; molecules; MRM; native tissue analysis; near-infrared spectroscopy; NF-κB; NO synthase; nutraceuticals; O-GlcNAcylation; obesity; osteoarthritis; osteochondral explant culture; oxidative stress; pathogenesis; pharmacological assay; physical activity; post-traumatic osteoarthritis; proteomics; Raman spectroscopy; regulation; remodeling; RNA-Seq; sex as a biological variable; SMAD2/3 signaling; TGF-β; therapy; type II collagen; vibrational spectroscopy; visfatin; vitamin C; vitamin D; whole transcriptome sequencing; Wnt/β-catenin
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication
• Physical Description: 1 online resource (306 p.)
• ISBN: 9783036534633; 9783036534640; books978-3-0365-3463-3
• Access: Open Access

In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.