Osteoarthritis: From Molecular Pathways to Therapeutic Advances

Osteoarthritis: From Molecular Pathways to Therapeutic Advances

In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.

Bibliographic Details
Format:	eBook
Language:	English
Published:	Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:	Biology, life sciences Research and information: general adipokines aging angiogenesis autophagy biomarker cartilage cartilage trauma celecoxib cell death chemokines chondrocyte chondrocytes chondrocytic commitment chondroitin chondroprotection collagen cytokines dietary supplements early diagnosis ECM exercise glucosamine glucosamine sulfate hexosamine biosynthetic pathway hyaluronic acid hydrostatic pressure hypertrophy IFNγ, IL-17 IL-1β IL-4 inflammaging inflammation infrared spectroscopy inhibitor Interleukin-1β joint modelling linker modifications matrix metalloproteinases mechanical loading meniscus mesenchimal stem cells methylsulfonylmethane microRNA miRNAs mitochondrial dysfunction MMP-13 molecules MRM native tissue analysis near-infrared spectroscopy NF-κB NO synthase nutraceuticals O-GlcNAcylation obesity osteoarthritis osteochondral explant culture oxidative stress pathogenesis pharmacological assay physical activity post-traumatic osteoarthritis proteomics Raman spectroscopy regulation remodeling RNA-Seq sex as a biological variable SMAD2/3 signaling TGF-β therapy type II collagen vibrational spectroscopy visfatin vitamin C vitamin D whole transcriptome sequencing Wnt/β-catenin
Online Access:	Open Access: DOAB: description of the publication Open Access: DOAB, download the publication

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Open Access: DOAB: description of the publication
Open Access: DOAB, download the publication