The Role of PPARs in Disease

The Role of PPARs in Disease

This reprint combines recent original manuscripts and reviews covering the multiple functions of peroxisome proliferator-activated receptors in physiology and pathophysiology. Potential applications and limitations of PPAR agonists and antagonists are discussed. All original contributions were publi...

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Bibliographic Details
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Medicine and Nursing
Physiology
addiction
adipogenesis
AKI
alcohol
Alzheimer's
Alzheimer's disease (AD)
angiogenesis
animal models
cancer
cellular metabolism
cilia
CKD
cognition
coronary artery
CYP450
cystogenesis
dominant-negative isoform
eicosanoids
endothelial cells
fatty acids
fetal programming
fibrosis
folate
growth suppressors
human studies
hypertrophic adipocytes
hypertrophic obesity
immortality
immune system
in vitro adipocytes
inflammation
inherited metabolic disorders
insulin-resistance
kidney
ligand
ligands
lipidomics
lipids
metabolic syndrome
metastasis
metastasis formation
modulators
nephron
nicotine
non-alcoholic fatty liver disease (NAFLD)
non-alcoholic steatohepatitis (NASH)
nuclear receptors
obesity
opioids
peroxisome proliferator activated receptors
peroxisome proliferator-activated receptor
peroxisome proliferator-activated receptor-γ coactivator-1α
peroxisome proliferator-activated receptors (PPARs)
peroxisome-proliferator activated receptors
PGC-1α, disease
pharmacology
PKD
PPAR
PPARG isoforms
PPARG splicing
PPARs
PPARα
proliferation
psychostimulants
resistance to cell death
risk factors
RNA sequencing
sex
Sirtuin1
synthetic agonists
therapy
toxicology
tumor angiogenesis
tumor progression
vascular
vitamin B12
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