The Role of PPARs in Disease

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine and Nursing; Physiology; addiction; adipogenesis; AKI; alcohol; Alzheimer's; Alzheimer's disease (AD); angiogenesis; animal models; cancer; cellular metabolism; cilia; CKD; cognition; coronary artery; CYP450; cystogenesis; dominant-negative isoform; eicosanoids; endothelial cells; fatty acids; fetal programming; fibrosis; folate; growth suppressors; human studies; hypertrophic adipocytes; hypertrophic obesity; immortality; immune system; in vitro adipocytes; inflammation; inherited metabolic disorders; insulin-resistance; kidney; ligand; ligands; lipidomics; lipids; metabolic syndrome; metastasis; metastasis formation; modulators; nephron; nicotine; non-alcoholic fatty liver disease (NAFLD); non-alcoholic steatohepatitis (NASH); nuclear receptors; obesity; opioids; peroxisome proliferator activated receptors; peroxisome proliferator-activated receptor; peroxisome proliferator-activated receptor-γ coactivator-1α; peroxisome proliferator-activated receptors (PPARs); peroxisome-proliferator activated receptors; PGC-1α, disease; pharmacology; PKD; PPAR; PPARG isoforms; PPARG splicing; PPARs; PPARα; proliferation; psychostimulants; resistance to cell death; risk factors; RNA sequencing; sex; Sirtuin1; synthetic agonists; therapy; toxicology; tumor angiogenesis; tumor progression; vascular; vitamin B12
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication
• Physical Description: 1 online resource (274 p.)
• ISBN: 9783036539911; 9783036539928; books978-3-0365-3991-1
• Access: Open Access

This reprint combines recent original manuscripts and reviews covering the multiple functions of peroxisome proliferator-activated receptors in physiology and pathophysiology. Potential applications and limitations of PPAR agonists and antagonists are discussed. All original contributions were published in Cells.