Advances and Novel Treatment Options in Metastatic Melanoma

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine and Nursing; ABT-737; acetazolamide; acetylcholine; adjuvant therapy; amoeboid motility; angiogenesis; apoptosis; arthralgia; Bcl-2 family; BCL2L10; biomarkers; BRAF; BRAF inhibitor; BRAF inhibitors; BRAF-mutant melanoma; cancer; cancer associated fibroblast; cancer stem cells; carbonic anhydrase; cell therapy; checkpoint inhibitor; cholinergic system; combined therapy; ctDNA; CXCL10; cyclopamine; cytokines; cytotoxicity; diagnosis; DOCK4; drug resistance; essential oils; exosomes; extracellular vesicles; FAK; hedgehog; HIPPO; HuR; immunity; immunotherapy; interferon; invasion; ipilimumab; lactate dehydrogenase; lipid metabolism; liquid biopsy; liver-directed-therapies; machine learning; MANS peptide; MARCKS; mechanism of action; melanoma; melanoma immune infiltrate; melanoma markers; melanoma metastasis; melanoma PDX; melanomagenesis; metalloproteinases; metastases; metastasis; metastatic dormancy; metastatic therapy; metastatic uveal melanoma (mUM); microenvironment; microRNAs; MITF; ML258; motility; mucosal melanoma; muscarinic receptors; n/a; nanoparticles; nicotinic receptors; nivolumab; OXPHOS; patient stratification; PD-1; pembrolizumab; phosphorylation; plasmacytoid dendritic cells; prediction; principal component analysis; prognosis; prognostication; protein tyrosine phosphatase; PTPs inhibitors; Rac1; radiotherapy; resistance; rheumatoid arthritis; sex-hormones; sex/gender; ShcD adaptor protein; siRNA; slow cycling phenotype; small molecules; SOCE; STAT3; Support Vector Machine; survival; target therapy; targeted therapy; targeted-therapy; therapeutic resistance; therapy; TLR; TPC2; tumor microenvironment; tumour microenvironment; uveal melanoma (UM); WNT5A
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication
• Physical Description: 1 online resource (528 p.)
• ISBN: 9783036533032; 9783036533049; books978-3-0365-3303-2
• Access: Open Access

The book presents several studies reporting advances on melanoma pathogenesis, diagnosis and therapy. It represents a milestone on the state of the art, updated at 2021, and also presents the current knowledge on the future developments in melanoma field.